With out sufficient NAD+, your physique’s sirtuin perform is proscribed as nicely. However fortuitously, it is potential to assist your NAD+ (and due to this fact, sirtuins) by supplementing with nicotinamide riboside5 (NR). “NR is a by-product of niacin (vitamin B3) and a precursor to NAD+,” explains Denniston. Within the physique, NR is transformed into nicotinamide mononucleotide (NMN) after which to NAD+, says Petersen. Due to their impact on NAD+, NR dietary supplements are often called NAD+ enhancers. Nonetheless, in an effort to successfully have an effect on your sirtuins, it is best to make use of high-quality NR dietary supplements, notes Petersen.
